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SIDE-EFFECTS OF THE SHINGLES VACCINE: SHOULD YOU GET IT?

by | Jan 13, 2023

Shingles is a painful rash caused by the varicella-zoster virus, the same virus that’s responsible for chickenpox. According to the Centers for Disease Control and Prevention (CDC), 1 in 3 people in the United States will develop shingles during their lifetime.

The CDC recommends that adults 50 years and older should get two doses of the shingles vaccine, called Shingrix, to prevent shingles and its complications. You should get Shingrix if you:

  • had shingles
  • received Zostavax (a shingles vaccine no longer in use in the U.S.)
  • received the chickenpox vaccine

While vaccination is important to prevent shingles, it can also cause certain side effects. Most common side effects after vaccination are mild, and go away on their own. Serious side effects from vaccines are extremely rare, with 1 to 2 people in every million showing any adverse reaction.

Therefore, you should always be prepared for possible side effects. This article informs you of the possible side effects of the shingles vaccine, including adverse reactions, and if you should get it.

Where do you get the Shingles vaccine?

You typically don’t require any appointment for the shingles vaccine. Shingrix is available in registered doctor’s offices and pharmacies.

How is the shingles vaccine given?

You will first be asked for some basic information, followed by showing your health insurance or the payment method.

The shingles vaccine is administered as an injection in your upper arm (shoulder). You will receive two doses of the vaccine, typically two to six months apart.

What is shingles?

Shingles is a viral infection that causes painful rashes to occur anywhere on your body. Also known as herpes zoster, shingles is caused by the same virus that causes chickenpox: the varicella-zoster virus.

Once you’ve had chickenpox, the varicella-zoster virus remains dormant in your nervous system even years after you have been cured of the infection. This virus can become active again at any point in your life, appearing in the form of shingles.

This infection is characterized by red skin rash and blisters that can appear anywhere on the body, but usually appear as a strip on one side – typically the face, neck, or torso.

The characteristic symptoms of shingles are:

  • redness of the skin in the affected area
  • itching or a burning sensation in an area
  • raised red rashes
  • fluid-filled blisters that break easily

Most cases of shingles clear up within 3 to 5 weeks. However, you can get shingles more than once in your lifetime.

How does the shingles vaccine work?

The shingles vaccine provides protection against shingles and significantly reduces the risk of complications, including postherpetic neuralgia (PHN), the most common complication of shingles.

According to the CDC, two doses of Shingrix can provide “strong protection” against it.

PHN occurs in the areas where the rash was even after it clears up, and can last for months or even years. It can cause, severe, long-term nerve pain.

According to a study, the rate of PHN after shingles increases with age:

  • a 5 percent risk in those younger than 60 years
  • a 10 percent risk in those aged 60 to 69 years
  • a 20 percent risk in individuals aged 80 years or older

The Shingrix vaccine is a non-live vaccine that contains parts of the causative virus. This allows the body to build up immunity against it.

According to the Food and Drug Administration (FDA), the Shingrix vaccine claims the following benefits:

  • reducing the incidence of shingles by 97 percent in individuals 50 and older
  • reducing the incidence of shingles by 90 percent in individuals 70 and older

Besides PHN, the shingles vaccine can protect you from other complications of shingles, including:

  • Eye damage. If the shingles rash appears on or near the eye, it can cause inflammation of the eye and its surrounding tissue. This condition is known as herpes zoster ophthalmicus (HZO).
  • Bacterial infections. The blisters caused by shingles can leave your skin tissue exposed, which can lead to bacterial skin infections.
  • Encephalitis. The shingles virus can cause inflammation of the brain. This condition is known as encephalitis and can cause severe headaches, confusion, memory loss, seizures, and even death.
  • Pneumonia. The varicella-zoster virus can also infect the lungs, which can lead to pneumonia.

Complications such as pneumonia, encephalitis, hearing problems, and death are rare complications of shingles.

Types of shingles vaccine

Shingrix is currently the only vaccine approved by the FDA.

According to the CDC, adults 50 years and older should get two doses of Shingrix, separated by 2 to 6 months. However, people with weakened immune systems can get the second dose 1 to 2 months after the first.

However, Shingrix is not the only vaccine available in other nations.

According to the National Health Service (NHS), there are two shingles vaccines used in the UK:

  • Zostavax. The FDA approved it in 2006 as a shingles vaccine, however, is no longer approved in the United States as of 2018.
  • Shingrix. Approved by the FDA in 2017 as a shingles vaccine.

According to the NHS, most people are administered the Zostavax vaccine, which is a live-attenuated vaccine. However, people with a weakened immune system are offered the Shingrix vaccine.

In most studies, the Shingrix vaccine is shown to be superior to the Zostavax vaccine in terms of its effectiveness and its ability to prevent complications.

Shingrix is currently the only vaccine approved by the FDA.

According to the CDC, adults 50 years and older should get two doses of Shingrix, separated by 2 to 6 months. However, people with weakened immune systems can get the second dose 1 to 2 months after the first.

However, Shingrix is not the only vaccine available in other nations. According to the National Health Service (NHS), there are two shingles vaccines used in the UK:

  • Zostavax. The FDA approved it in 2006 as a shingles vaccine, however, is no longer approved in the United States as of 2018.
  • Shingrix. Approved by the FDA in 2017 as a shingles vaccine.

According to the NHS, most people are administered the Zostavax vaccine, which is a live-attenuated vaccine. However, people with a weakened immune system are offered the Shingrix vaccine.

In most studies, the Shingrix vaccine is shown to be superior to the Zostavax vaccine in terms of its effectiveness and its ability to prevent complications.

Shingles vaccine side effects

According to the CDC, you are likely to have temporary side effects from getting the Shingrix vaccine shots. These side effects might affect your ability to do normal daily activities for 2 to 3 days.

Mild side effects

At most instances, the shingles vaccine does not produce any side effects. However, some people might experience some mild side effects, which may include:

  • pain, redness, and swelling at the injection site
  • sore arm
  • muscle pain
  • gastrointestinal problems
  • tiredness
  • headache
  • fever and shivering
  • upset stomach

Besides these, some people may experience side effects from the Shingrix vaccine that can prevent them from doing regular activities. Most symptoms go away on their own in 2 to 3 days.

If you do experience these side effects, you can take an OTC pain medication for some relief.

Severe side effects

If you are allergic to any of the ingredients in the shingles vaccine, you could develop a severe, life-threatening allergic reaction. This is known as anaphylaxis, and it can be fatal if not treated immediately.

According to the CDC, only one or two people for every million doses of the vaccine show any serious reactions.

The signs of an adverse reaction are:

  • swelling of the face, tongue, or throat
  • hives
  • difficulty breathing
  • rapid or irregular heartbeat
  • dizziness
  • confusion or anxiety

If you experience any of these symptoms, you should seek immediate medical assistance. Someone who has a history of severe allergies or has experienced an anaphylactic shock before should always carry an EpiPen for emergency situations.

Guillain-Barré syndrome (GBS) is another rare yet adverse side effect of the shingles vaccine. It is a rare autoimmune disorder that damages the body’s nerves. Early symptoms of GBS include weakness and tingling, usually beginning in the legs. In severe cases, it can lead to paralysis.

Any adverse reactions to the Shingles vaccine should be reported to the Vaccine Adverse Event Reporting System (VAERS). Your healthcare provider will usually file this report, or you can do it yourself by visiting the VAERS website or calling 1-800-822-7967

Should you get the shingles vaccine?

Almost 1 out of every 3 people in the United States will develop shingles in their lifetime. The risk of getting shingles increases as you get older and about 1 to 4 percent of people get hospitalized due to complications of shingles.

With older adults the most likely to get shingles, the CDC recommends two doses of the shingles vaccine for adults 50 years and older.

Currently, Shingrix is the only shingles vaccine approved by the U.S. Food and Drug Administration (FDA). Meanwhile, the Zostavax vaccine is still in use in countries like the United Kingdom.

According to the CDC, the shingles vaccine helps you prevent future occurrences of the disease, as well as its complications.

You should get Shingrix even if in the past you:

  • had shingles
  • received Zostavax
  • received the chickenpox vaccine

Shingrix is a high rate of success in terms of preventing shingles and its complications. According to the CDC, it claims:

  • a 96.6 percent efficacy in adults aged 50 to 59 years
  • a 97.4 percent efficacy in adults aged 60 to 69 years
  • a 91.3 percent efficacy in adults aged 70 years and older

The vaccine also significantly prevents the chance of developing postherpetic neuralgia (PHN):

  • 2 percent effective in adults aged 50 years and older
  • 8 percent effective in adults aged 70 years and older

Besides older adults, it is also recommended that adults aged 19 years and older with weakened immune systems because of disease or therapy should also get two doses of Shingrix.

The effectiveness of the vaccine in individuals with weakened immune systems is:

  • 2 percent among adult autologous hematopoietic cell transplant recipients
  • 2 percent in a post hoc efficacy analysis of adult patients with hematologic malignancies
  • 5 percent in a post hoc efficacy analysis of adult patients with immune-mediated diseases who were not taking immunosuppressive medication

The Shingrix vaccine is not recommended for individuals younger than 50 years with a healthy immune system. There is no maximum age limit for getting the shingles vaccine.

Should you avoid the shingles vaccine?

While the CDC recommends the shingles vaccine for everyone aged 50 years and older, there are certain cases when a person should avoid getting the vaccine:

  • Allergies. The shingles vaccine contains certain ingredients that may cause an allergic reaction in some people. If you have ever had a severe allergic reaction to any ingredient of the vaccine or after the first dose of Shingrix, you should avoid it.
  • Pregnancy or breastfeeding. The safety of the shingles vaccine during pregnancy has not yet been established. As a result, pregnant or breastfeeding women should avoid getting the vaccine.
  • Ongoing infection. It is recommended to avoid the vaccine during an ongoing infection because your immune system may be compromised. If you have a minor illness, such as a cold, you may get the shingles vaccine. However, you should wait until you recover if you have a moderate or severe illness.
  • Weakened immune system. People with a weakened immune system due to some disease or treatment (such as AIDS or chemotherapy) should be especially careful before getting the vaccine.
  • If you test negative for the varicella-zoster virus. People who test negative for the varicella-zoster virus should get the chickenpox vaccine instead.
  • Those who currently have shingles.

In all cases, it is a good measure to take a doctor’s advice before getting the shingles vaccine.

Frequently asked questions

How many shingles shots do you need?

The CDC recommends adults 50 years and older get two doses of the shingles vaccine (Shingrix), spread 2 to 6 months apart.

Which shingles vaccine is the best?

Shingrix is currently the only available shingles vaccine in the United States. It boasts a high efficacy of over 90 percent in preventing shingles and its complications like postherpetic neuralgia.

Is the shingles vaccine covered by Medicare?

According to the CDC, the Medicare Part D plans cover the shingles vaccine, although there may be a cost to you depending on your plan. It also mentions that Medicare Part B does not cover the shingles vaccine.

Is Shingrix good for your lifetime?

Immunity stays strong for at least the first 7 years after vaccination. There is no current recommendation for booster doses.

How much does the shingles vaccine cost?

According to Shingrix, 90 percent of privately insured patients 50 years and older pay no or limited out-of-pocket costs, with the average cost being less than $50 per dose. The retail cost for the shingles vaccine is $162 per shot.